Random Pearls of Anesthesia by Dr Maryam Malik (1)

****Nitrous oxide****

# 30% in combination with 20% oxygen particularly use in Dental Surgery.
#Rapid onset and Recovery
# A/E causes diffusional hypoxia
# t1/2 is 3-5 mins
# Good Analgesia but weak Anesthesia
# Least Hepatotoxic & Safest Inhaled Anesthetic
# likely Require Administration of Muscle Relaxant
****Halothane****
# Vagomimetic causes atropine sensitive bradycardia
# Inhaled anesthetic with highest solubility in Blood
# Causes Maximum Cerebral flow
# Decompose due to light
# not use in close circuit Absorption
# Mix with “NO” to give Maximum effect
****Desflurane****
#Use As anesthetic for out patient Surgery
# Irritate Larynx
# More pungent
# MAC <1
#Agent with minimum Blood gas solubility coefficient
*****ISO FLURANE****
# MAC 0.6-1.6 [ in mcq 1.2]
#Of choice in Chronic Renal Failure & Ischemic Heart Disease
# Not Increase Intracranial Pressure
Note=) Des and IsoFlurane require Special Vaporizer
***** SEVOFLURANE****
# smooth, fast pleasant Induction
# Agent of choice in Childern
#A/E can induce epilepsy
# Coronary Steal Syndrome
# Require Normal Vaporizer
*****BUPIVACAINE*****
# Most toxic, Myocardial toxic local Anesthesic
# long acting Local Anesthetic
# Highest Protein binding
#Safe dose 2.5 mg/kg
# 2% in a vial of 4ml = 80mg
#A/E overdose causes early cardiac arrythmia.
******KETAMINE******
# Dissociative Anesthesia
#Increase HR,CO,BP
# C/I in Hypertensive Patient & with IntraCranial HTN.
# Profound Analgesia
# causes all except Confusion

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