Past Paper of FCPS Part 1 Medicine October 2007

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Medicine October 2007

Q.1 Paracetamol…..

 

  1. a) increases PT
  2. b) its overdose causes Nephrotoxicity
  3. c) is a poor anti-inflamatory
  4. d) is more stronger than codeine
  5. e) causes met-Hb.emia more frequently than Phanacetin

 

Q.2 ATN is associated with…

 

  1. a) Hyperkalemia
  2. b) conc. urine in initial stages
  3. c) increase in s.urea but normal s.creatinnine

d)

 

Q.3 Congenital cataract is associated with

 

  1. a) chiken pox
  2. b) chromosomal abnormality
  3. c) small pox
  4. d) Rubella

 

Q.4 MS is characterized by…

 

  1. a) Lewy bodies
  2. b) Patchy demylination& white fiber gliosis
  3. c) axonal neuropathy

d)

 

Q.5 All of the following have ability of phagocytosis EXCEPT

 

  1. a) Microgila
  2. b) Lymphocytes
  3. c) Kuffer cells
  4. d) Neutrophils

 

Q.6 Pulmonary Arterial pressure increases with..

 

  1. a) Essential HPTN
  2. b) Sympthatic stimulation
  3. c) Nitroglycerine
  4. d) Excercise
  5. e) Hypoxia

 

Q.7 in an Asthamticfemale,immeditae treatment of HPTN during intra-operative HPTN, is

  1. a) sublingual glycerine trinitate
  2. b) intra.venousnitroglycerine
  3. c) propranalol

d)

 

Q.8 During giving local anaestheia, the long needle goes far into greater palatine canal,causing anaesthesia of an autonomic ganglion,as a result along with dryness of nasal mucosa also occurs

 

  1. a) decreased secretions of Parotid
  2. b) decreased secretion of Submandibular & sublingual glands

c)

 

Q.9 Tissue which has in-ability to replace dead cells

 

  1. a) Heart
  2. b) Kidney
  3. c) Liver
  4. d) Bone
  5. e) Bowl Mucosa

 

Q.10 Non-essential amino acid includes

 

  1. a) Leucine
  2. b) Iso-leucine
  3. c) Methionine
  4. d) Tyrosine

 

Q.11 Metabolic Alkalosis is caued by

  1. a) Chronic Hypoventilation
  2. b) Pancreatic Fistula
  3. c) hyperglycemia
  4. d) ATN

 

Q.12 Glucronide conjugation of drugs

  1. a) causes inactivation of drug
  2. b) is Type 1 reaction
  3. c) makes drug insoluble in water
  4. d) increases its effects

 

Q.13 A patient having generalized body weakness & numbness,

on investigation he is having Un-conjugated Bilirubinemia,

Hb= 7.4 md/dl MCV..> 120 fl,

theanemia is due to ….

  1. a) Hemolysis
  2. b) Vit B 9 def.
  3. c) Vit B 12 def.
  4. d) Hypersplenisim

 

Q.14 Tissue with Dual autonomic supply but not reciprocal suuply is

  1. a) Skin
  2. b) Blood vessels
  3. c) Pupil
  4. d) Salivary glands
  5. e) Ciliary muscle

 

Q.15 Cause of joint pain in Deep sea divers

  1. a) arterial embolism
  2. b) venous embolism
  3. c) DIC
  4. d) thromboembolism

 

Q.16 In summer,in a fasting man the cause of concenterated urine is

  1. a) Skin
  2. b) Blood vessels
  3. c) Pupil
  4. d) Salivary glands
  5. e) Ciliary muscle

 

Q.15 Cause of joint pain in Deep sea divers

  1. a) arterial embolism
  2. b) venous embolism
  3. c) DIC
  4. d) thromboembolism

 

Q.16 In summer,in a fasting man the cause of concenterated urine is

  1. a) ADH
  2. b) No Oral intake
  3. c) Aldosterone
  4. d) increased sweeting

 

Q.17 A 35 yr old man is having bilateral ptosis of eye during evening since last few weeks,the confirmatory test of the diagnosis will be

  1. a) Tensilon Test
  2. b) Ach Receptor Antibody Test
  3. c) blood culture
  4. d) CT scan Brain

 

Q.18 if a High Dextrose water is infusion given to a person,it inhibits

  1. a) Cotisol
  2. b) ADH
  3. c) Aldosterone
  4. d) Insulin

 

Q.19 Parasympthatic supply of Sigmoid Colon is

  1. a) Sacral segments S2,S3,S4
  2. b) Pelvic splanchnic Nerves
  3. c) vagus nerve

d)

 

Q.20 which does not take part in inflamatory reactions

  1. a) Adrenaline
  2. b) Histamine
  3. c) 5-hydroxy tryptamine
  4. d) Dopamine

 

  1. 21 Parietal & Visceral Pericardium is supplied by
  2. a) Phrenic Nerve
  3. b) Sympthatic Nerves
  4. c) Vagusneve
  5. d) Cardiac Plexus

 

Q.22 A young man had sinjury to the neck with sum sharp object,3yrs ago,

Now he notices a bulging swelling above the clavicle on sneezing & coughing,

this swelling most probably due to…

  1. a) Injury to deep fascia of neck
  2. b) demage to supra-pleural membrane
  3. c) Un-united first Rib Fracture

 

Q.23 Middle meningeal artery if ruptured while meinges are intact,the Haemorrhage will be

  1. a) Epidural
  2. b) Subdural
  3. c) Intracranial

d)

 

Q.24 Dorsal Rami of the cervical nerves innervates

  1. a) Abductor Pollices
  2. b) Extensors of Limbs
  3. c) Extensors of Trunk
  4. d) Stabilizers of Shoulder

 

Q.25 Muscles of Hand supplied by

  1. a) ventral rami of C-8
  2. b) Ventral branches of T-1
  3. c) Median Nerve
  4. d) Ulnar Nerve
  5. e) Radial Nerve

 

Q.26 A person has sharp knife injury to upper medial aspect of arm,

after which He is unable to Flex his elbow & having loss of cutaneous sensations on lateral aspect of forearm,

the nerve injured is

  1. a) Median Nerve
  2. b) Axillary nerve
  3. c) Radial Nerve
  4. d) Musculocutaneous Nerve

 

  1. 27 A Transplant from identical twin is
  2. a) Allograft
  3. b) Heterograft
  4. c) Homograft
  5. d) Isograft
  6. e) Xenograft

 

Q.28 Therapeutic Index of a drug indicates its

  1. a) Effectivity
  2. b) Efficacy
  3. c) Potency
  4. d) Toxicity

 

Q.29 Pharmakokinetic interaction among drugs is examplifiedby :

  1. a) Shortening of action of Procaine by Adrenaline
  2. b) increase peripheral toxicity of Levodopa with Carbidopa
  3. c) increase toxicity of Methotrexate by Aspirin
  4. d) prevention of Nitroglycerine induced tachycardia by Propranolol
  5. e) blokade of acetylcholine receptors by atropine

 

Q.30 A 30 years old 75 kg Diabetic man with recent diagnosis of Hypertension,

On ECG : Left Ventricular Hypertrophy

s.Urea — 20 mg/dl s.Creatinine — 0.7 mg/dl

s.Uric Acid– 7.5 mg/dl s.Na — 140 mmol

  1. K– 2.5 mmols.Cl — 103 mmol

s.HCO3 — 23 mg/dl 24 Hr Urinary Proteins– 30

& Fasting BSL— 80 mg/dl

The cause is…….

  1. a) Essential HPTN
  2. b) Diabetic Nephropathy
  3. c) Pheochromocytoma
  4. d) Addison Disease
  5. e) Primary HyperAldosteronism

 

Q.31 Acute Tubular Necrosis is characterized by

  1. a) Hyper-kalemia
  2. b) Initially concenterated urine
  3. c) Metabolic Alkalosis
  4. d) s.Urea is increased &s.creatinine is normal

 

Q.32 GFR is measured by clearance of

  1. a) Inulin
  2. b) Creatinine
  3. c) Urea
  4. d) Glucose

 

Q.33 Sarcoidosis is diagnosed microscopically by

  1. a) Granuloma with Asteroid
  2. b) Non-caseating Granuloma
  3. c) Caseating Granuloma
  4. d) Macrophages & Giant cells

 

Q.34 Multipule sclerosis is characterized by…

  1. a) Lewy Bodies in Neucleus
  2. b) Ptachydemylination with white fiber gliosis
  3. c) Axonal degeneration

d)

 

Q.35 What is INAPPROPRIATE about Vagus Nerve..

  1. a) its longest Cranial Nerve
  2. b) passes in between IJV & ICA
  3. c) passes posterior to Carotid Sheath
  4. d) Gives Recurrent Laryngeal Nerve
  5. e) gives Superior Laryngeal Nerve

 

Q.36 Thymus is

  1. a) Rich in Lymphocytes
  2. b) Present at birth but shorlyregree after birth
  3. c) derived from 4th Pahryngeal Pouch
  4. d) is a part of Thyroid
  5. e) Lies posterior to Trachea

 

Q.37 True statement about Down Syndrom is

  1. a) Trisomy 23
  2. b) contains single X chromosome
  3. c) more chances with increasing maternal age

 

Q.38 Kleinifilter syndrome

  1. a) contains single X chromosome
  2. b) less chances of Mental retardation
  3. c) phenotypically female

 

Q.39 Following is Autosomal Dominant Disorder

  1. a) Phenylketonuria
  2. b) Hereditary Spherocytosis
  3. c) Hemophilia A
  4. d) Cystic Fibrosa

 

Q.40 At 35 weeks of Gestation,in sample taken from amniocentesis,

there is increased Alpha-Fetoprotein,its most probable cause is..

  1. a) Down syndrome
  2. b) Turner syndrome
  3. c) SpinaCystica
  4. d) Hydrocephalous

e)

 

Q.41 Thoracic Duct….

  1. a) recieves Lymph from both right & left sides
  2. b) lies in posterior mediastinum
  3. c) passes just right to the thoracic aorta
  4. d) extends from upper abdoment to neck
  5. e) has a dilatation called Cisterna

 

Q.42 Rate of passage of food in esophagus depends upon

  1. a) Gravitational Force
  2. b) Neuromuscular excitation different @ upper & lower oesophagus
  3. c) progressive peristalsis in esophagus
  4. d) Acidity

 

Q.43 @ Leprotomy Retroperitoneal Abscess was found,the site woud be

  1. a) Stomach
  2. b) Sigmoid Colon
  3. c) Transverse Colon
  4. d) Ascending Colon
  5. e) Small intestine

 

Q.44 Source of Estrogen& Progesterone in last trimester is

  1. a) Chorionic Villus
  2. b) Placenta
  3. c) Overy
  4. d) Adenohypophysis
  5. e) Corpus Leuteum

 

Q.45 A patient having Facial deviation along with loss of sensations on anterior 2/3 rd of tongue,theleision lies in

  1. a) Facial Canal
  2. b) Internal auditary meatus
  3. c) Facial Nerve Nucleus
  4. d) Stylomastoid Foramen

 

Q.46 All are the branches of Vagus nerve EXCEPT

  1. a) Auricular
  2. b) Lacrimal

c)Pharyngeal

  1. d) Recurrent Laryngeal

 

Q.47 Following nerve lies in the Cavernous Sinus

  1. a) Opthalmic
  2. b) Occulomotor
  3. c) Abducent
  4. d) Trigeminal

 

Q.48 In a Pituitary Adenoma,theBitemporal Hemianopia occurs due to leison of

  1. a) Central part of Optic chiasma
  2. b) Optic Nerve
  3. c) Optic Tract
  4. d) peripheral Part of Optic chiasma
  5. e) Lateral Geniculate body

 

Q.49 Muscle of Forced Expiration is

  1. a) Internal Intercostal
  2. b) External Intercostal
  3. c) Sternoceidomastoid
  4. d) Scalenus Anterior
  5. e) ScalenusMedius

 

Q.50 Na Retension is associated with

  1. a) Dehydration
  2. b) increase ADH
  3. c) Decreased Aldosterone
  4. d) Heart Failure
  5. e) Hyperthyroidism

 

Q.51 Von-Willebrand Disease is

  1. a) Autosomal Dominant
  2. b) Autosomal Recessive
  3. c) in some family members asoociated with Factor IX deficiency
  4. d) in some family members associated with normal Factor IX

 

Q.51 A male wd A+ (Ao,DD) Blood group, married to a female having

B+ (Bo,Dd ) blood group,children can have all blood gp EXCEPT

  1. a) AB +ve
  2. b) AB -ve
  3. c) A + ve
  4. d) B +ve
  5. e) O -ve

 

Q.52 Vital Capacity

  1. a) measured directly by Spirometry
  2. b) is decreased in some Lung diseases
  3. c) is the sum of Tidal Volume+ERV+IRV

 

Q.53 When a branch of Pulmonary Artery is blocked by embolus,following Lung function increases

  1. a) Alveolar Co2
  2. b) Alveolar O2
  3. c) Pulmonary artery O2
  4. d) Pulmonry artery Co2
  5. e) Ventilation Perfusion

 

Q.54 Difference between Adenoma & Hyperplasia is

  1. a) increase in size of cell
  2. b) increase in No. of cells
  3. c) Capsule

d)

Q.55 In a CLD patient presenting with Haematemesis,the preferred immediate treatment is

  1. a) Octeriotide
  2. b) Vit K
  3. c) formed Platelet Conc.
  4. d) PPI

e)whole blood

Q.56 Among most important initial steps in apoptosis

  1. a) Activation of Bcl-2 Receptors
  2. b) Activation of Caspases
  3. c) Water influx into the cell

d)

Q.57 After a trauma, a person has inability to stand from sitting position,

the nerve demaged is

  1. a) Infragluteal
  2. b) Supragluteal
  3. c) Schiatic
  4. d) Femoral
  5. e) Obturator

 

Q.58 About K – Regulation , following is correct

  1. a) K is 98% in the cells
  2. b) normally completely reabsorbed in Distal tubule
  3. c) increase water affects K-balance
  4. d) decrease in D.K

 

Q.59 A man with persistant fits without regaining consciousness for 30 minutes,

the immediate treatment is with

  1. a) Carbamazepine
  2. b) Valporate
  3. c) Lorazepan
  4. d) …….

Q.60 An unconsious man with pin-point pupils not responding to Naloxone,the probable cause is

  1. a) Heroin
  2. b) Hasheesh
  3. c) Morphine
  4. d) Phenobarbitone

 

Q.61 Stomach gets its arterial supply from all EXCEPT

  1. a) Ceiliac artery
  2. b) Splenic Artery
  3. c) Superior Mesenteric Artery
  4. d) Hepatic Artery

 

Q.62 The Hormone which stimulates release of HCO3 from Pancreas without stimulating pancreatic enzyme secretions,is

  1. a) CCK
  2. b) Secretin
  3. c) Gastrin
  4. d) Pepsin
  5. e) Mucin

 

Q.63 Supra-Renal Gland arterial supply

  1. a) recieves all braches directly from Aorta
  2. b) recieves blood from 3 sources
  3. c) recieves branches from both renal arteries
  4. d) recieves blood from inferior phrenic artery

 

Q.64 Stenson’s duct

  1. a) arises from posterior surface of Parotid
  2. b) pierces the Buccinator muscle
  3. c) opens in the oral cavity against ….

 

Q.65 Which infection is not caused by DNA virus

  1. a) Chicken Pox
  2. b) Herpes Simplex
  3. c) Herpes Zoster
  4. d) Mumps
  5. e) Small Pox

 

Q.66 On examination of a female,a plaque like leision seen on Postero-superior aspect of Vagina,it is

  1. a) Squamous Cell CA
  2. b) Adenocarcinoma
  3. c) Rhabdomyosarcoma
  4. d) wart

 

Q.67 About CSF most appropriate statement is

  1. a) it is ultrafilterate of Plasma
  2. b) has more glucose than blood
  3. c) hascushioing effect
  4. d) absorbed in Choroid Plexus

 

Q.68 On standing from a sitting position,@ apex of lung there is increase in

  1. a) Blood Flow
  2. b) Ventilation
  3. c) pO2
  4. d) pCO2

 

Q.69 Metastatic Calcification occurs mostly in

  1. a) Kidney
  2. b) Bone
  3. c) Lung
  4. d) Intestine
  5. e) Pancreas

 

Q.70 Basal Cell Carcinoma involves

  1. a) Buccal Mucosa
  2. b) Hard Palate
  3. c) Soft Palate
  4. d) Lower Lip
  5. e) Oral Cavity

 

Q.71 A female underwent Gastrectomy for Zollinger-Ellison Syndrome,given Parenteral Vit B-12,

the inability to absorb B-12 is due to loss of…

  1. a) Parietal Cells
  2. b) Gastric Cells
  3. c) Cardiac Ceells

 









 

 

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