Past Paper of FCPS Part 1 Medicine November 2011

FCPS PART1 MEDICINE PAPER NOVEMBER 2011

1-Following is realted to myxoid degeneration

a-Mitral valve prolapse (Robins)

b-libman sac endocarditis

 

2-about azathioprine,

a-converted to active metabolite by xanthine oxidase

b-does nor affect cells of bone marrow

C-fis dihydrflorate reductase

 

3-nerve supply of plantar surface of foot

a-superficial peroneal

b-deep peroneal

c-sural nerve

d-posterior tibial

 

4-which of following causes increased interstitial pressure

a-increased capillary permeability

b-increased colloid osmotic pressure

 

5-lesion of Right optic tract ( came 2 times in paper 2)causes

a-left homonymous hemianopia

 

6-which structure arches over root of right lung

a-azygous vein

b-hemiazygous vein

c-arch of aorta

d-esophagus

 

7-Superficial cardiac plexus in superior mediastinum isformed by

a-branches of right vagus

b-branches of left vagus(Grays)

 

8-which antiemetic has highest bioavailability..(oraldrug bioavailability in brackets I found)

a-ondansteron(56-71%)

b-cyclizine(80%)

c-droperidol(protein bindind 85-90% so less availablty)

d-metoclopramide(65-95%)

e-porcholrperazine(12.5%)

 

9-which is not bleeding profile screening test

a-PT

b-APTT

c-BT

d-CT

e-measurement of Antithromib III

 

10-A person is asked to bring down fully abducted arm slowly…but when he tries, limb falls suddenly…which muscle is diseased/paarlysed?

a-deltoid

b-subscaoularis

c-pectoralis major

d-teres major

 

11-Which antithyroid drug is safe in pregnancy?

a-propylthiouracil

b-methemazole

c-radioactive iodine

 

12-abscess in posterior triangle of neck operated .now patient cant comb her hair..where is lesion?

a-radial nerve

b-axillary nerve

c- spinal accessory nerve(http://en.wikipedia.org/wiki/Posterior_triangle_of_the_neck)

 

13-Isoniazid

a-its toxicity reduced by pyridoxine

 

14-middle meningeal artery is branch of

a-maxillary artery

 

15-Anterior and Posterior spinal arteries arise from

a-Vertebral and PICA respectively

 

16-Initial Most sensitive test for SLE

a-ANA

 

17-patient with dry eye and dry mouth..most specific test

a-Anti ds DNA

b-Anti ss DNA (Its Sjogren syndrome)

 

18-cimetine n ranitidine both have the same mechnism of action..ranitidine is superior because?

a.has more bio availability

b.has less CNS side effects

c.has rapid onset of action

d.has more affinity

 

19-9 year child suddenly died.. on autopsy, coronary artery aneurysm

a-kawaski disease

 

20-most abundant immunoglobulin

a-IgG

 

21-IgE is found on surface of which

a-Basophil

b-Eosinophil?

 

22-RBCs

a-are biconvex

b-rich in glycolytic enzymes

c-have nucleus

 

23-17 year old primigravida, which of following if present against Rubella is indication of termination of pregnancy

a-IgG (can be from past infection)

b-IgM (Current infection)

c-IgA

 

24-HbsAg negative, Anti-Hbc TOTAL reactive, Anti-HBc IgM non reactive, Anti-Hbe reactive…whats the inference?

a-Past exposure to HBV

b-immunized

c-incubation period

d-active disease

e-Recover phase (CMDT 2012)

 

25-If patient is HIV seropositive , whats is best approach?

a-repeat test with other other methods

b-correlate with history

c-isolate him

d-decalre AIDS

 

26-9 year old girl who is terminally ill..asks u “am I gonna die”? child’s parents have already told u not to inform her about diagnosis .whats best approach?

a-“don’t worry. you will be fine”

b- you will die

c-“what have ur parents told u”

d-most kids survive

 

27-Atypical mycobcateria

a-most uncommon

b-resistant to common ATT

c-heal rapidly

d-cause only lung disease

 

28-heart sound produced by vibrations by filling of ventricle is

a-1st

b-2nd

c-3rd

d-4th

5-murmur

 

29- regarding heart sounds ,

a-S1 is high pitch

b-produced by atrial kick is S3

c-ear can detect sound b/w 40 cycles/sec to 500cycles/sec (Ganong)

d-second heart sound relatively louder

 

29-Cervical cancer is associated with

a-HPC 16

b-HPV 6

 

30-premalignant intra epithelial lesion of vulva

a-pagets disease

 

31-Pansystolic murmur in kid after 5 weeks of birth and cyanosis

a-VSD

 

32-When aorta and pulmonary trunk does not separate in

a-Truncus arteriosus

 

33-Atrail fibrillation

a-pulse deficit

b-multiple p waves

c-regular QRS complex

 

34-at common dose,tachycardia is effect of which drug

a-isosorbide dinitrate

 

35-which drug is not calcium channel block but given in angina is

a-metoprolol

 

36-study in which we have two groups diseased and non diseased person…we have to evaluate cause by history..type

a-case control

 

37-sample which is age based grouped…then random people taken from each group..type

a-random campling

b-stratified random sampling

 

38-vitamin deficiency by avidin

a-biotin

 

39-hormone which causes storage of carbohydrates,proteins and fat

a-insulin

b-GH

 

40-Stress response…which hormone is not released

a-cortisol

b-insulin

c-ADH

d-GH

 

41-Lysomsomes

a-arise from golgi apparatus

b-have catalase and hydrolase

c-have oxidase which generate H2O2

 

42-Epithelium of larynx

a-startified squamous

b-pseudostartified columnar ciliated

 

43-Which cell release extracellular fibers and amorphous substance

a-Fibroblasts

 

44-Which cell is not a part of epidermis

a-pacinian corpuscle

b-merkle cellc-melanocyets

 

45-Which is not “BASIC TISSUE”

a-blood

b-muscle

c-nerve

d-epithelium

 

46-Achondroplasia (a 50 yrs man with short stratue n short upper n lower limbs… with lumber lordosis) is

a-autosomal dominat

b-autosomal recessive

 

47-most common genetic diseases are

a-chmosomal

b-x-linked recessive

c-autosomal recessive

d-autosonal domiante-multifactorial

 

48-Test in cystic fibrosis .. Child has multiple episodes of respiratory infction,otitis media..family history of same disease..

a-sweat chloride test

 

49-Superior parathyroid

a-is at mid of posterior border of thyroid at first tracheal ring

 

50-Thyroid

a-moves with deglutition because its attached with prevertebal facia

b-lymph drains to deep cervical lymph nodes

 

51-Vitamin A source

a-carrots

 

52-Patient is taking immunosupresants…now has neck rigidity, CSF has high WBC mostly lymphocytes..on microscopy,organism has halo around it..causes

a-cryptococcosis

b-toxoplasmosis

c-histoplasmosis

d-candida

 

53-which crosses with simple diffucsion

a-Urea

b-Na

c-K

d-Glucose

 

54-Glucose is transposrted in kidney by

a-simple diffusion

b-facilitated diffusion

c-primary active transport

d-secondary active transport

 

55-Glucose transport across a membrane is directly proportional to conc gradient..type of transport is

a-simple diffusion

b-facilitaed

c-active

 

56-Number of structural genes is

a-5000-10,000

b-20,000-25,000

 

57-to prevent autodigestion of pancreas,pancreatic enzymes are secreted

a-bound to protein

b-secrted in preform to be activated by trypsin

 

58-Corpus callosum

a-connects 2 cerebral hemispheres

 

59-Lateral wall of third ventricle

a-made by medial 2/3 of thalamus

 

60-In long term memory

a-structural changes in synapses

b-presynpatic potentiation

 

61-Baby has hemolytic disease.Blood group is B +..With which blood u will do exchange transfusion

a-B negative

b-O

c-AB

d-B+

e-any Rh + blood

 

62-Nornal FEV1/FVC ration

a-0.6

b-0.8

 

63-Functional Residual capacity is

a-air left at end of tidal expiration

 

64-Stab above xiphisternal at 6th costal cartilage just to right,what will be damaged

a-right ventricle

b-right atrium

c-IVC

 

65-Rectus sheath

a-incomplete above umbilicus

b-contains superior and inferior gastric arteries

c-starts at level of arcuate line

 

66-What is true

a-Rectum ends at rectal folds’

b-Upper limit of rectum is in front of 2nd coccygeal vertebra

c-anal canal is region between anus and where levator ani passes around rectum

d-inferior rectal vein drains into portal vein

 

67-Patient with neck rigidty,CSF protein 400mg/dl.Glucose 40 mg, WBC raised 400lymphocyte..Diagnosis

A-TBM

b-bacterial mengintits

c-viral meningitis

d-encaphilitis

 

68-Which is osmotic diuretic?

a-Mannitol

b-acetazolamide

 

69-EBV is associated with which CA

a-Nasopharyngeal

 

70-Coronary blood supply is regulted by

a-duration of diastole

b-local myocardial metabolism

 

71-Which one has no effect on coronary circulation?

a-Parasympathetic nerve supply

b-Heart rate

 

72-What is released at pain inhibitory fibers when they contract with incoming fibers

a-Substance P

b-serotonin

c-Glutamate

d-enkaphlin

 

73-What is effect of TCA antidepressant overdose?

a-seizures

b-HTN

 

74-What muscle abducts femur at hip joint?

a-gluteus maximus

b-gluteus medius

c-gluteus minimus

 

75-Effect of parasympathic?

a-constrics muscle in iris

 

76-Visual acuity?

a-increased by foveal cones

b-normal even if colour vision is lost

 

77-Cardiac output increased in?

a-exercise

b-pregnancy

 

78-Pulse pressure?

a-determined by stroke volume

(http://en.wikipedia.org/wiki/Pulse_pressure)

b-measured only in diastole

 

79-Regarding adrenal coretx

a-Adrenal cortex essential for life

b-Medulla is essential for life

 

80-Fight and flight reponse results in

a-Decreasd airway resistance

 

81-Transverse fibers in pons make

a-Superior cerebellar penducle(CP)

b-Inferior CP

c-Middle CP (snell)

d-Olivary tract

 

82-Spaciticity in mid-collicular decerebrate lesion is LEAST LIKELY due to

a-Increased activity of gamma motor nuron

b-increased activity of inhibitory inter neuron

c-medullary activity

 

83-B/L complete loss of all sensations below lesion occurs when there is lesion of

a-Ipsilateral cord transection

b-ipsilateral Thamalus lesion

c-Complete Cord transection

 

84-Patient has right arm, leg paralysed. Right plantar upgoing, Reflexes exaggerated..Lesion is in?

a-Left internal capsule

b-Right cortex

 

85-Pupils accommodate but don’t react to light ..Lesion is in

a-Pretectum

b-edinger westphal nucleus

 

86-A man from AJK had fever with chills for last 6months.he suddenly died of cough..On autopsy, bloodclots in peritoneum..daignosis/

a-malaira ?

b-leshmenia

C-sickle celle anemia

 

87-a 2 year old girl from Azad Kashmir presented with off and on fever..looks pale..has pancytopenia and hepatosplenomegaly ESR 80,,,she has

a-Acute lymphoblastic leukemia

b-gauchers

c-visceral leishmaniasis

(Muzafarabd has highrevalance of leshmania and it do causes pancytopenia.Ref Jewetz micro)

 

88-Highest amont of triglyceride in

a-chylomicron

 

89- about primitive streak

a-site of involution of epiblast to make mesoderm

b-formed in first week

c-formed in 2nd week

 

90-Right brachiocephalic vein

a-is shorter than left

 

91-Chorionic villi

a-attach chorion to endometrium

b-are called primary villi when they have mesodermal core

 

92-In a premature child,which does not close mostly

a-Ductus arteriosus

b-Foramen ovale

 

93-Which does not produce hormones

a-small cell lung CA

b-Teratoma

c-chorioccarcinoma

d-chondrosarcoma

e-arhenoblastoma(secrets testosterone)

 

94-A patient has lung abscess..develops meningitis..causes is

a-Pneumococcis

b-H.Influenze

c-Streptococci

d-staphylococcus

 

95-A patient has cervical lymphadenopathy..shows granoluma..which is necessary for TB diagnosis(2 questions)

a-Caseous necrosis

 

96-Bell’s palsy..lesion is at

a-stylomastoid foramen

b-geniculate ganglion

c-befor giving branch to stapedius

 

97-First response to vessel injury

a-activation of extrinsic pathway

b- activation of intrinsic pathway

c-platlet activation

d-vessel constriction

 

98-Prostacyclin is secreted by

a-Thrombocytes

b-Vascular endothelium

 

99-Mantoux test is

a-type 4 hypersensity reaction

 

100-Which is related to Type 3 hypersensitivity reaction?

a-Arthus phenomenon

 

101-Regarding MRSA, which is LEAST APPROPRIATE

a-Vancomysin is given to all contacts

b-test all contacts

c-isolate patient

d-isolate the organism

e-subtyping the organism

 

102-Basal cell CA is least likely related to

a-Smoking

b-white shkin’

c-brown iris

d-Clest phlogeny

 

103-Which is not premalignant Leukoplakia precursor

a-Spices

b-syphilis

c-spirit

d-sexual contact

e-chronic infection

 

104-in typhoid fever,test in first week is

a-Blood culture

b-Stool culture

c-Urine Culture

d-Widal

 

105-Lobar Pneumonia is diagnosed by

a-Blood culture

b-Spututm culture

 

106-Stony dull percussion on anterior chest indicates

a-Fluid in pleural cavuty

 

107-if pleura is ruptured there is:

a-inward collapse and inward chest wall spring

b- inward collapse and outward chest wall spring

c- outward collapse and outward chest wall spring

d- outward collapse and inward chest wall spring

 

108-Lymph is filtered in

a-Lymph nodes

b-spleen

c-Thymus

 

109-Which area has least metastasis

a-liver

b-lung

c-brain

d-lymph node

e-spleen

 

110-Cells is thymus which have least affinity for MHCclass 1 develop into

a-delta cell

b-T helper 1 cell

c-T helper 2 cell’

d-NK cell

 

111-Which is pronounced in Penicillin Anaphylaxis

a-Bronchospasm

b-fever

c-generalized skin rash

 

112-Enzemye is serotonin,epinephrine metabolism….??/

a-MAO

b-COMT

c-dopamine hydroxylase

 

113-Regarding type 1 hypersensitivty,

a-Rheumatoid arthritis is not type 1

 

114-A person died of CA colon..autopsy showed thousands polyps..his father died of same disease..polyps are which type

a-Adenomatous

 

115-Ionizing radiation injury??/

A-FREE redical

 

116-Fluid which has 0.5 GRAM/dl protein is

a-Saliva

b-Lacrimal fluid

c-Lymph

d-CSF

 

117- A female jaundice, ALT 17, Alk phos 75, Retics10…Cause of jaundice is

a-Hemolytic anemia

 

118-patient died of CRF ..which tissue will be seen Hypertrophied on autopsy?

a-Parathyroid

 

119-A 59 year female, known hypertensive taking medications presented to emergency in unconscious state..Serum Potassium is 5..Diagnosis?

a-ARF

b-CRF

 

120-In the presence of ADH, in which segment filtrate will be isotonic to plasma

a-Ascending loop of henle

b- Descending loop of henle

c-Cortical Collecting duct

d-Medullay Collecting duct

e-Renal pelvis

 

121-Which is not character of MALIGNANT tissues?

a-Fibrous reaction around tumor

b-increased Nuclear to cytoplasmic ratio

c-Abnormal mitosis

d-Anaplasia

 

122-Hormone which is abundant in Fetus but in adults level increase with advancement of CA Colon is

a-HCG

b-CEA

c-Alpha Fetoprotein

 

123-Left adrenal vein drains into

a-Left renal vein

 

124-Which is not related to anterior relation of right kidney?

a-asceding colon

b-descending colon

c-liver

 

125-Small intestine brush border DOES NOT play role in digestion by one of following reaction

a-Protects epithelium

b-secretes enzymes

c-faciltates transports

d-increases surface area

e-increases movement of intestine

 

126-Following does not affect Volume of distribution

a-age

b-sex

 

127-In elderly male

a-There is decreased elasticity of Myocardium

b-diastolic hypotension

c-Systolic hypotension

 

128-Aldosterone

a-causes its affect by increasing Potassium permeability

 

129-Thirst is stimulated by

a-Extracellular dehydration

b-Intercellular dehydration

 

130-Aldosterone is increased in response to

a-decreased volume

b-taking ACE inhibitor

c-corticosterone

 

131-Blood flow to muscle is increased by

a-Norepinephrine

b-guanathidine

 

132-Decreased extracellular Calcium

a-reduced reuptake of transmitter

b-Reduced release of neurotransmitter from presynaptic vesicle

 

133-Increased Serum Ca does not causes

a-Nerve hyper excitability

 

134-Magnesium is stored in

a-Bones

b-muscles

 

135-Hyperparathyroisim does not cause

a-Demineralization of bone

b-kidney stone

 

136-when mean arterial pressure reduces from 100 to 85,one of following DOES NOT OCCUR

a-muscle blod flow decreases in 20 min

b-GFR is maintained

c-CNS ischemic reaction occurs

 

137-CSF

a-has cushioning effect

 

138-patient has chest pain..ST elevation in V1.2.3.,4..

a-Anteroseptal MI

b-anterolateral

 

139-Most specific cardiac marker

a-troponin T

b-ck mb

c-myoglobin

d-ldh

 

140-A girl in PT prade has developed dyspnea…few months back she had sour throat…now what best test to start

a-ASO titre

b-Blood culture

 

141-Which is NOT necessary for liver to be declared chronic diseased?

a-Acute inflammation

b-loss of total liver architecture

c-Fibrosis

d-disruption of portal blood flow

e-regernearting nodules

 

142-Female has jaundice, hepatosplenomegaly, Xanthomas…what test will be Confirmatory?

a-Anti mitochondrial antibody

b-ALT

c-AST

d-CT scan abdomen

e-USG abdomen

 

143-A quack has given drug to patient after which he developd jaundice..test

a-Alanine transaminase

b-aspartate transaminase

 

144-Female patient cough,hemoptysis,..Renal biopsy shows flat Ig A deposit

a-Goodpasture

b-FSGS(IgA Nephropathy was not in option)

 

145-Hyopnatremia develops in

a-CHF

b-SIADH

 

146-Aldosterone acts by

a-Gene activation

b-c AMP

c-IP3

 

147-patient has skin pigmentation at elbows and exposed parts.. BP 90/60, K is 2.5..dioagnosis

a-addison

b-cushings

 

148- Which drug to give in diabetic gastropathy?

a-metachlorpramide

b-domerperidone

 

149-patient breathing deep,resp rate 6/mi..which drug poisoning?

a-morphine

b-pethidine

c-nalbuphine

d-pheobarbitone

 

150-pateint had retrosternal pain..biopsy from esophagus showed columnar epithelium..its called

a-barrets esophagus

b-esophagitis

c-

 

151-a patient is having Glycosuria..blood glucose is100..diagnosis

a-Diabetes

b-proximal tubule no reabsorbing glucose

c-LOW renal threshold

 

152-Manoux test negative in TB patient…causes

a-taking immunosuppresants

 

153-artery which crosses third part of duodenum

a-superior mesenteric

b-inferior mesenteric

c-left colic

 

154-Achalsia cardia

a-decreased ganglion cells of vagus in muscle

b-increased number of neurons

c-occurs only at pharyngoesophagus junction

 

155-basal rhythm of small inetsine

a-correlated with stomach

b-decreased when mechanical motilityy starts

c-variable affected by hormones

d-constant in duodenum variable elsewhere

 

156-If vagotomy done

a-Gastric acid seretin increases

b-Gastric pepsin increases

c-Gasric emptying decreases

 

157-patient hb 6,dysphagia..cause

a-iron deficiency anemia

b-vitamin b12 deficiency

 

158-Regarding platlets

a-formd by fragmentation of megakarycoytes in bone marrow

 

159-What is not true regarding von Wilibranddisease?

a-autosomal dominat

b-autosomal recessive

c-some family member have normal factor 9

d- some family member have decreased factor 9

e-genetic inheritance

 

160-patient has pancytopenia..test to do (detail needed)

a-bone mwrow biopsy

 

161-Anticoagulation is contraindicated in

a-Thrombocytopenia

b-Hypertension

c-Cerebral infarction

 

162-Trunk muscle supplied by

a-posterios primary ramus

b-posterior cutaneous nerve

 

163-What is fast neuron?

a-A alpha

b-A beta

C-A delta

d-C fiber

 

164-Person naked in room ..tempertutre 21 degree centigrade..humidity 80..loss of heat by

a-insensicble perspiration

b-sweating

c-conduction and radiation

d-urination

 

165-Afluent Aphasia is lesion of (2 questions?)

a-Broca area

 

166-Left shift of oxygen curve

a-haldane effect

b-bohr effect

 

167- Anterior inferior cerebellar artery is branch

a-basillar artery

 

168–Mandible joins midline

a-symphsis

b-symdesmosis

 

169-Least moveable joint

a-symphysis

b-ball and socket

c-Saddle

 

170-Neuron in olfactory

a-bipolar

b-sustentaticualr

c-brush border

 

171-IN CHRONIC RESPIRATORY ACIDOSIS, HOW MUCH HCO3 RISE OCCURS FOR 10 MMHG OF PO2 ?

a-1 mEQ

b-3 mEq

c-7 meq

d-10meq

e-15 meq

 

172-A patient has fever,weight loss,cough…whats necessary for TB diagnosis? (TB Q came 2 times)

a-isolation of organism

b-caseous necrosis

 

173-A lesion of brocas area causes

a-aphasia

b-anosmia

 

174- Lesion of right optic tract causes visual loss (options were wrong)

a-right temporal left nasal

b-bitemporal hemianopia

 

175-LYMPHATIC DRAINGAGE OF LOWER LIP

a-submental & submandibular

b-submental and supraclavicular

 

176-Which cell produces Histamines

  1. a) Fibroblast
  2. b) Mast cells
  3. c) Lymphocytes
  4. e) Neutrophil

 

177-.lesion of optic chiasm due to pituitary tumour

a.causes bitemporal hemianopia.

 

178-Regarding growth Hormone

a.its  polypeptide

  1. initiate growth of bone n cartilage by sometomedin
  2. half life is 20 to 60 min in circulation

 

179-.Na is absorbed along basolatral membrane by?

  1. Na K pump
  2. Na glucose cotransport

 

180-Amino acids are absorbed from kidney to blood by

  1. primary active transport
  2. simple diffusion

c-secondary active transport

 

181-carcinoma is not related to:

  1. Iron deficiency
  2. Iodine deficiency

 

182-clinically cental cyanosis occur when hb become more than

a-1 g/dl

b- 5 g/dl

c-3 g/ dl

 

183-vertebral column

a-31 vertebrae

b-7 cervical vertebrae

 

184-Best approach to patient

a-start with open ended questions

b-start with closed ended questions

c-start by asking presenting complaint

d-start by asking his name,age

 

185-Plasma osmolilaity decreased by giving

a-0.9 % Nacl

b-isotonic glucose

c-vasopressin

 

186-Which drug used in Subarachnoid hemorrhage?

a-Nimodipine

 

187-Regarding bronchopulmonary segment

a-its functional unit

b-its anatomical unit

c-its functional,anatomical and surgical unit

 

188-Pressure in aorta is maximum during

a-rapid ejection phase

b-isovolumetric contraction

c-isovolumetric relaxation

 

189-in all types of shock

a-there is decreased celluar oxygenation

b-dec CO,

c-hypovolemia

 

190-Prenatal diagnosis of thalassemia

a-by chorionic villous sampling

 

191-19 year old male with bruising..only platlets low all else reports normal..diagnosis

a-ITP

 

192-A patient has come to ER with heart rate of 40/min..diagnosis?

a-first degree heart block

b-2nd degree

c-3rd degree heart block

 

193-a question related to diuretic therapy..dont remember exactly

 

194-pitutary tumor..visual loss????

a-bitemporal hemianopia

 

195-enterogastric reflex is not stimulated by

a-pancreatic secretions in small intestine

b-when chime enters duodenum

 

196-Regarding anti-emetics

a-Ondansterone is effective in cytotoxicity induced vomiting more than metoclopramide

 

197-Muscular tissue derived from

a-Mesoderm

b-Endoderm

c-Ectoderm

 

198-Regarding Thyroid

a-drains into deep cervical lymph nodes

 

199–Cervical cancer is associated with

a-HPV 16

b-HPV 6

 

 

 

 









 

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