Synopsis on “CARDIOVASCULAR RISK FACTORS IN TYPE 2 DIABETIC PATIENTS WITH ISCHAEMIC HEART DISEASE”
|Introduction / Background
Diabetes Mellitus (DM) is a clinical syndrome characterized by absolute or relative deficiency of Insulin. Lack of insulin affects the metabolism of carbohydrates, proteins and fat and causes a significant disturbance of water and electrolytes homeostasis and so profound effects on cardiovascular system1. Diabetes is world-wide in distribution and the incidence of both type 1 and 2 is rising. It is estimated that in the year 2000,150 million people world-wide had diabetes and this is expected to double by 2010, 1. Ischaemic heart disease (IHD) is a syndrome which remains a major cause of death world-wide. It includes Angina Pectoris, Acute Myocardial Infarction and sudden cardiac death. As per WHO Report 55/100000 of American die of IHD and 45.3% of all deaths in USA are due to IHD 2. The major risk factors that predispose to atherosclerosis and IHD have been identified by means of number of prospective studies in well established population groups 3-5. Ischaemic heart disease accounts for higher mortality in type 2 DM 6. In the UK prospective diabetes study after 9 years of follow up, IHD events were 70 times more frequent than other diabetic complications. The annual average mortality rate is double than that in non diabetic people 7. Many studies have been conducted at international level to analyze risk factors in developing IHD in diabetic population 3-6 and there are also few studies at national level 8-9. My study is designed to investigate the presence of risk factors in type 2 diabetic population i.e. dyslipidemia, hypertension and smoking to analyze their significance as risk factors in development of IHD among diabetics.
The objective of this study is to; determine presence of dyslipidemia, hypertension and smoking among diabetics with IHD as compared to those who do not develop IHD in patients presenting at department of medicine Holy Family Hospital.
|Material and Methods|
|Similar Preliminary Studies
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9. Khan MS, Moin S.Prevalence of cardiovascular risk factors in type 2 Diabetic patients with Ischaemic heart disease. Pak Armed Forces Med J.2005;55(1):8-1
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